The Monastery of Panagia Spiliani of 1600, patroness saint of Nisyros, is located west of Mandraki and it is adjacent to the castle, while virtually hanging in the air. The catholic of the church is shaped in the natural cave cavity with built-in parts from early Christian churches, while the wood curved temple has additions by a later marble temple. The 18th century icon of Panagia has an older depiction of Agios Nikolaos at the back. You can reach the monastery by climbing the 130 steps that start from Lagkadi, from the side of the sea.